A bioreactor is a type of fermentation vessel that is used for the production of various chemicals and biological reactions.
It is a closed container with adequate arrangement for aeration, agitation, temperature and pH control, and drain or overflow vent to remove the waste biomass of cultured microorganisms along with their products.
A bioreactor should provide for the following:
- Agitation (for mixing of cells and medium),
- Aeration (aerobic fermentors); for O2 supply,
- Regulation of factors like temperature, pH, pressure, aeration, nutrient feeding, and liquid leveled.
- Sterilization and maintenance of sterility, and
- Withdrawal of cells/medium
Bioreactors are used for the production of biomass, metabolites, and antibiotics.
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